The purpose of this study was to investigate fairness and responsibility as predictors of academic integrity among lecturers in public universities in Oyo State, Nigeria. Five hundred participants constituted the study’s sample, out of whom only 485 were used after data administration. Both the independent and dependent variables were measured with validated instruments with 0.87 reliability co-efficient and the data obtained was analysed using the Pearson product moment correlation (PPMC) statistical method. Two research hypotheses were formulated and tested at 0.05 level of significance. The result showed that there was a significant relationship between fairness and academic integrity among university lecturers (r= .774; p<0.05) as well as between responsibility and academic integrity among university lecturers (r= .459; p<0.05). The implication of this showed that fairness and responsibility had significant impacts on academic integrity among university lecturers. In view of these findings, it was recommended that educational stakeholders should intensify their effort to institute a culture of fairness in the institution so as to improve on the level of academic integrity among lecturers.